陈静(邮箱:dr_chenjing@njucm.edu.cn),博士,博士后,副教授,硕士研究生导师,医学院生物化学与分子生物学学系专任教师,江苏省研究型医院学会肺结节和肺癌MDT专业委员会委员。
主要从事恶性肿瘤的分子调控机理研究,发表SCI文章30余篇,发表杂志涉及《Molecular Cancer》、《Drug Resistance Update》、《Clinical and Translational Medicine》、《Cancer Letters》《Journal of pharmaceutical analysis》等,他引超过1500次,单篇最高他引超过150次。主持课题2项,申请并授权专利7项。
代表性论文:
1、ZHU C, XIE Y, LI Q, ZHANG Z, CHEN J, ZHANG K, XIA X, YU D, CHEN D, YU Z, CHEN J. CPSF6-mediated XBP1 3'UTR shortening attenuates cisplatin-induced ER stress and elevates chemo-resistance in lung adenocarcinoma[J]. Drug Resist Updat, 2023, 68: 100933.
2、JIANG M, QI F, ZHANG K, ZHANG X, MA J, XIA S, CHEN L, YU Z, CHEN J, CHEN D. MARCKSL1-2 reverses docetaxel-resistance of lung adenocarcinoma cells by recruiting SUZ12 to suppress HDAC1 and elevate miR-200b[J]. Mol Cancer, 2022, 21(1): 150.
3、CHEN H, ZHAO L, MENG Y, QIAN X, FAN Y, ZHANG Q, WANG C, LIN F, CHEN B, XU L, HUANG W, CHEN J, WANG X. Sulfonylurea receptor 1-expressing cancer cells induce cancer-associated fibroblasts to promote non-small cell lung cancer progression[J]. Cancer Lett, 2022, 536: 215611.
4、ZHANG K, CHEN J, LI C, YUAN Y, FANG S, LIU W, QIAN Y, MA J, CHANG L, CHEN F, YANG Z, GU W. Exosome-mediated transfer of SNHG7 enhances docetaxel resistance in lung adenocarcinoma[J]. Cancer Lett, 2022, 526: 142-154.
5、CHEN J, ZHANG K, ZHI Y, WU Y, CHEN B, BAI J, WANG X. Tumor-derived exosomal miR-19b-3p facilitates M2 macrophage polarization and exosomal LINC00273 secretion to promote lung adenocarcinoma metastasis via Hippo pathway[J]. Clin Transl Med, 2021, 11(9): e478.