刘阳(邮箱 liuyang@njucm.edu.cn), 博士,副教授,硕士生研究生导师。现为中国药理学会神经精神药理学青年委员会委员、江苏省免疫学会委员。主要从事神经系统疾病包括帕金森病和抑郁症的病理机制研究,发现与确证潜在的药物治疗靶点。主持国家自然科学基金青年基金1项,参与国家自然科学基金重大项目、国家自然科学基金重点项目各1项。在Autophagy、Acta Pharmaceutica Sinica B、EMBO Reports等高水平学术杂志发表研究论文10余篇,授权中国发明专利1项。目前担任European Journal of Pharmacology、Phytomedicine等学术杂志审稿专家。
代表性研究论文
1. Liu Y, Liu T, Zhou Y, Li W, Wang M, Song N, Zhang W, Jiang J, Yuan S, Ding J, Hu G*, Lu M*, Impeding the combination of astrocytic ASCT2 and NLRP3 by Talniflumate alleviates neuroinflammation in experimental models of Parkinson’s disease, Acta Pharma Sin B, 2023; 13(2):662-677.
2. Zhou Y#, Liu Y#, Kang Z, Yao H, Song N, Wang M, Song C, Zhang K, Ding J, Tang J*, Hu G*, Lu M*, CircEPS15, as a sponge of MIR-24-3p ameliorates neuronal damage in Parkinson disease through boosting PINK1/PRKN-mediated mitophagy. Autophagy, 2023; 19(9):2520-2537.
3. Jiang S#, Tian T#, Li W#, Liu T, Wang C, Du R*, Liu Y*, Lu M*, Mefloquine targets NLRP3 to reduce lipopolysaccharide-induced systemic inflammation and neural injury, EMBO Rep, 2023; 24(10): e57101.
4. Song Q#, Lin L#, Chen Y, Qian J, Wei K, Su J, Ding J, Lu M, Liu Y*, Tan R*, Hu G*, Characterization of LTr1 derived from cruciferous vegetables as a novel antiglioma agent via inhibiting TrkA/PI3K/AKT pathway, Acta Pharmacol Sin, 2023;44(6):1262-1276.
5. Su J#, Yang P#, Xing M, Chen B, Xie X, Ding J, Lu M, Liu Y*, Guo Y*, Hu G*, Neuroprotective effects of a lead compound from coral via modulation of the orphan nuclear receptor Nurr1, CNS Neurosci Ther, 2023; 29(3):893-906.