阮秦莉(ruanql@njucm.edu.cn),博士,副教授,硕士研究生导师,医学院•整合医学学院公共卫生学系教师。2000年本科,2004年硕士毕业于西安交通大学,2011年博士毕业于东南大学。主要开展中药活性成分对退行性疾病药物作用靶点,中药配伍的作用机制研究。主持国家自然科学面上基金1项,国家自然科学青年基金1项,参与国家重点基础研究发展计划973项目,及国家级和省部级科研课题10余项,发表多篇学术论文。研究方向:中药复方和单体联合治疗多种退行性疾病(包括阿尔兹海默症,帕金森病,卵巢储备功能下降)的药理机制和作用靶点。
主讲本科课程:预防医学,卫生统计学。是国家一流本科课程《预防医学》的主要团队成员。参编《预防医学》教材1部。
部分文章列表(#为通讯作者):
1.Zheng Zihui, Wu Kanglu, Ruan Qinli#, Li Dongfang, Liu Weizhen, Wang Min, Li Yaoyao, Xia Jintao, Yang Dongqing, Guo Jun. Suppression of Selective Voltage-gated Calcium Channel Alleviates the Neurodegenerative Dysfunctions through Glutathione S-Transferase-mediated Oxidative Stress Resistance in AD Caenorhabditis elegans. Oxidative Medicine and Cellular Longevity, 2022
2.Zhang Xiaolong *, Ruan Qinli *, Lu Dandan, Zhai Yiqian, Li Chen, Fu Yahan, Zheng Zihui, Song Ying, Guo Jun#. Baicalein inhibits non-small-cell lung cancer invasion and metastasis by reducing ezrin tension in inflammation microenvironment. Cancer Science, 2020, 7, 1-11
3.Ruan QinLi#, Xu Yun, Xu Rui, Wang Jiaying, Hua Yongqing, Wang Meng, Duan Jinao. The Adverse Effects of Triptolide on the Reproductive System of Caenorhabditis elegans: Oogenesis impairment and decreased oocyte quality. International Journal of Molecular Sciences, 2017, 18, E464
4.Ruan Qinli, Qiao Yan, Zhao Yunli, Xu Yun, Wang Meng#, Duan Jinao#, Wang Dayong#, Beneficial effects of Glycyrrhizae radix extract in preventing oxidative damage and extending the lifespan of Caenorhabditis elegans. Journal of Ethnopharmacology, 2016,177:101-110
5.Ruan Qinli, Ju Jingjuan, Li Yunhui, Li Xiaoba, Pu YuePu, Wang Dayong, Liu Ran, Liang Geyu, Zhang Juan, Yin Lihong#, Chlorpyrifos exposure reduces reproductive capacity owing to a damaging effect on gametogenesis in the nematode Caenorhabditis elegans. Journal of Applied Toxicology, 2012, 32(7): 527-535
6.Ruan Qinli, Ju Jingjuan, Li Yunhui, Liu Ran, Pu Yuepu, Yin Lihong#, Wang Dayong, Evaluation of pesticide toxicities with differing mechanisms using Caenorhabditis elegans. Journal of Toxicology and Environmental Health, Part A, 2009, 72(11-12): 746-751
7.Ma Xinfei, Ruan Qinli, Ji Xiaotian, Yang Ju, Peng Huiping#. Ligustrazine alleviates cyclophosphamide-induced hepatotoxicity via the inhibition of Txnip/Trx/NF-κB pathway. Life Sciences.2021.274
8.阮秦莉,俞辰亚代,华永庆,王梦,段金廒,雷公藤甲素对模式生物雄性秀丽隐杆线虫的生殖毒性作用,中成药,2018,40(5):1005-1014
9.阮秦莉*, 许云, 葛恒菊, 郭盛, 华永庆, 王梦. 补肾活血汤对雷公藤甲素致卵巢储备功能下降秀丽隐杆线虫生育力的影响. 中药药理与临床, 2017, 33(04): 105-110.